Edwards' Analytical takes great pride in its suite of testing laboratories. Combining a scientific approach across a range of instrumentation and testing techniques with highly skilled and experienced laboratory scientists, we offer the highest standard of analytical services.

Our laboratories are split into the three scientific disciplines:




Want to find out more? Click on a particular technique.


This series of techniques is used for the separation and analysis of, often complex, mixtures in a sample. By dissolving the sample in a fluid or gas (called the mobile phase),  the various constituents of the sample, when passed through a medium of another material (called the stationary phase),will travel at different rates, causing them to separate. Such retention analytes from the stationary phase can then be further analysed to gain information on the sample's composition.

At Edwards' Analytical we offer two main types of chromatography analysis - gas and liquid introduced through a variety of auto samplers including headspace and heated injection:

Gas Chromatography(GC)

Our detectors include Mass Spectrometer (MS) and Flame Ionisation (FID). These techniques are used for the analysis of volatile organic compounds for purity assaying. We also use our GC-MS and and Thermal Conductivity Detector (TCD) for the determination of the purity of gasses.

Liquid & Size Exclusion Chromatography(HPLC)

Using Refractive Index (RI), Ultra-violet (UV), and Fluorescence, we can determine characteristics of non-volatile and inorganic liquid samples; for example, analysing complex mixtures for purity, monitoring processing systems during manufacture, and post-cleaning validation. This technique is used extensively for analysis of specific migration of extractable additives from plastic packaging into food and pharmaceutical products.

Size exclusion chromatography is used at Edwards' Analytical for the analysis of molecular weight distribution of polymers, especially organic-solvent soluble compounds.

These techniques are used primarily for the analysis of inorganic elements, from 100% right down to single Parts Per Trillion (PPT).

Atomic Absorption Spectroscopy (AAS)

Set up for elemental analysis in line with current testing monographs in the respective pharmacopeia, the AAS is a workhorse for large quantities of routine single element analysis where high precision is essential.


Our NEXION-300x’ HPLC-ICP-MS enables analysis of over 70 elements (metallic and inorganic) over a wide range of concentrations from high Parts Per Million (PPM) to single Parts Per Trillion (PPT).

Recognising the need for flexibility, the ‘NEXION-300x’ offers analysis for a collision cell and a true reaction cell with quadrupole scanning to bring together the two most powerful polyatomic interference removal techniques in the same instrument.

We are able to offer clients the choice of which mode is best suited for the study depending on the level of interference removal and detection limits required.

Furthermore, as the ‘NEXION-300x’ has been integrated with a liquid chromatography platform, we can offer the complete solution for the separation and determination of individual metal compounds. Therefore we will be able to identify “what forms” of a species are present in a sample and not just “how much”, allowing us to identify the exact toxicity and nature of the elements in question. We can even quantify elements in organic solvents by direct injection!


The ED-XRF is equipped with a high-speed mapping function; our SEA6000VX enables complex measurement of inorganic materials from 100% to 100 PPM concentrations, which has otherwise been difficult with conventional XRF analysers. This system will meet your requirements by measurement of microscopic areas without disassembling the product and create area maps to identify regions of hazardous substances.

With the SEA6000VX we can carry out in-depth analysis of much smaller areas, as small as 0.5 - 2mm; in the same measurement time, other conventional equipment would need 10 times that sample size.

Features include:

  • High-speed integrated mapping measurement
  • High-speed precision micro-spot analysis of film thickness and composition
  • High-resolution imaging system with wide coverage
  • Large, non-destructive sample holder enabling high-resolution mapping of large samples (20x30cm area)
  • Helium purge chamber for analysis of elements down to sodium


Fourier-Transform Infrared (FT-IR) Spectroscopy with 3D mapping microscope with ATR mapping crystal

This is the mainstay method for the analysis and identification of organic molecules and compounds. The IR-microscope accessory allows us to map areas of complex materials such as multi-laminate film or contaminants (and even cross sections of hair) down to 0.5-micron spot-size.

The equipment is also available for the analysis of microscopic contaminants in powders, liquids and pharmaceutical preparations, and for forensic type applications.

We have online access to numerous databases, through which we can obtain information on standards, test methods, polymer and packaging suppliers and material data sheets and specifications.

Ultra-Violet / Visible (UV-VIS) Spectroscopy with integrating sphere

Edwards’ Analytical uses this method for identification of compounds, colours and opacity/translucence of materials.

This branch of our testing service considers a material's macroscopic characteristics with the application of physical laws and analytical instrumental practices.

Areas of examination include:

Intermolecular forces that act upon the physical properties of materials (plasticity, thermal dynamics and surface tension in liquids)

Reaction kinetics

The effects of ions on the electrical conductivity of materials

Surface chemistry and electrochemistry of materials

This area of material science is employed to understand how a material or product behaves under the influence of the temperature dynamic.

Differential Scanning Calorimitry (DSC): used to calculate the enthalpies of transitions of a material, with temperature represented as endothermic or exothermic reactions. This technique can be used to determine  melting point, glass transition point, and onset of oxidation. It is particularly useful for assaying relative densities of polymers and purities of pharmaceuticals.

Thermal Mechanical Analysis (TMA):  used to examine a material's coefficient of linear thermal expansion with temperature. In other words, how it changes shape with heat over time. Particularly useful for understanding the cross-linking of thermo-plastics, including rubbers, or crystal lattice forms.

Thermal Gravimetric Analysis (TGA): this determines the change in weight of a sample in relation to a temperature regime with time. This technique is extremely precise in quantifying volatile constituents of a material, and is particularly useful for determining the  percentage moisture and residual solvents.

Differential Mechanical Thermal Analysis (DMTA): this technique is used to characterise materials - namely polymers for their visco-elastic properties. With this technique a test specimen is subjected to a sinusoidal stress, which allows the strain in the material to be studied. By adjusting the temperature of the sample chamber and the frequency of movement of the stress, it enables us to identify clearly the glass transition of the material and transitions corresponding to other molecular motions.

Suppository testing: is offered in compliance to the EP monograph 2.9.2 for resistance to rupture and softening temperature using our bespoke test equipment.


Edwards' Analytical has extensive laboratory resources dedicated to testing material and product characteristics using traditional diagnostic and quantitative techniques, often as part of raw material, API and finished product pharmacopoeial and proprietary testing methods:

Water content (Karl Fischer) for micro moisture content and  moisture weight loss by evaporation


Specific Density


Specific Optical Rotation

Classical wet chemistry techniques, including: titration; saponification, hydroxyl and iodine values; loss on ignition and ignition point testing; non-volatile residue; and hydrolytic resistance of glass

We are very pleased to announce Edwards' Analytical are working along side Axis Test Laboratories based at Unit 11A, Oaklway Court, Meadowfield Industrial Estate, Meadowfield, Durham, DH7 8XD


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